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Microdontin A and B: Two New Aloin Derivatives from Aloe microdonta.

Authors
  • Farah, M H
  • Andersson, R
  • Samuelsson, G
Type
Published Article
Journal
Planta medica
Publication Date
Feb 01, 1992
Volume
58
Issue
1
Pages
88–93
Identifiers
PMID: 17226442
Source
Medline
License
Unknown

Abstract

The leaf juice of ALOE MICRODONTA Chiov. is used in Somali traditional medicine as a remedy for jaundice and for topical treatment of skin diseases. Mucilage was precipitated from the fresh juice by addition of ethanol and the supernatant chromatographed on Amberlite XAD-2 to yield a fraction containing anthraquinone derivatives. Flash chromatography on silica gel followed by preparative TLC yielded aloin A and a new compound. Spectral data (mass, (1)H- and (13)C-NMR) identified this compound as a mixture of aloin A and B where the glucose of both compounds is esterified with 4-hydroxycinnamic acid at the 6'-position. The two compounds were denoted as microdontin A and B, respectively.

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