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MIC versus MBEC to determine the antibiotic sensitivity of Staphylococcus aureus in peritoneal dialysis peritonitis.

Authors
  • Girard, Louis P
  • Ceri, Howard
  • Gibb, Allan P
  • Olson, Merle
  • Sepandj, Farshad
Type
Published Article
Journal
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
Publication Date
Jan 01, 2010
Volume
30
Issue
6
Pages
652–656
Identifiers
DOI: 10.3747/pdi.2010.00010
PMID: 21148059
Source
Medline
License
Unknown

Abstract

In PD peritonitis that is long standing, recurrent, or not responsive to therapy, MBEC testing should be considered as a biofilm may be present. Gentamicin should be strongly considered over other agents for empiric gram-negative coverage as it may be providing synergy in the setting of Staphylococcus aureus. Also, the newer anti-staphylococcal drugs should be tested for their performance in a biofilm using the MBEC method.

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