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[The methylation and mRNA expression of SLC5A8 and TMS1/ASC genes in human glioma].

Authors
  • Jiang, Zheng
  • Li, Xin-gang
  • Hu, Jin
  • Lu, Da-ru
  • Zhou, Wei
  • Jiang, Yu-quan
  • Li, Chao-yue
Type
Published Article
Journal
Zhonghua yi xue za zhi
Publication Date
Jan 30, 2007
Volume
87
Issue
5
Pages
292–297
Identifiers
PMID: 17456354
Source
Medline
License
Unknown

Abstract

Hypermethylation of SLC5A8 and TMS1/ASC genes in the promoter regions may play an important role in the down-regulation of their mRNA levels in glioma. The methylation frequency and mRNA levels of SLC5A8 or TMS1/ASC genes are closely related to the malignant development of glioma.

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