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[Methotrexate: How long between administration and conception?]

Authors
  • Elefant, E1
  • 1 Centre de référence sur les agents tératogènes (CRAT), DMU ESPRIT, épidémiologie et biostatistique, santé publique, pharmacie, pharmacologie, recherche, information médicale, thérapeutique et médicaments, GHU APHP Sorbonne Université, site Trousseau 26, avenue Dr-Netter, 75571 Paris cedex 12, France. Electronic address: [email protected] , (France)
Type
Published Article
Journal
Gynecologie, obstetrique, fertilite & senologie
Publication Date
Nov 06, 2020
Identifiers
DOI: 10.1016/j.gofs.2020.11.004
PMID: 33166704
Source
Medline
Keywords
Language
French
License
Unknown

Abstract

In women of childbearing age, methotrexate is prescribed in many indications other than cancer, either chronically (psoriasis, rheumatoid arthritis, IBD, etc.) or occasionally (ectopic pregnancies). The time given to these patients to consider pregnancy is currently subject to great variability depending on the sources. Analysis of the available objective evidence suggests that it is not justified to unnecessarily lengthen this period, and that conceiving the menstrual cycle following stopping methotrexate is quite possible. Copyright © 2020. Published by Elsevier Masson SAS.

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