Affordable Access

Methotrexate for corticosteroid-resistant polymyalgia rheumatica and giant cell arteritis.

Authors
  • Krall, P L
  • Mazanec, D J
  • Wilke, W S
Type
Published Article
Journal
Cleveland Clinic journal of medicine
Publication Date
May 01, 1989
Volume
56
Issue
3
Pages
253–257
Identifiers
PMID: 2743546
Source
Medline
License
Unknown

Abstract

Three patients (one with polymyalgia rheumatica with jaw claudication and two with biopsy-proven giant cell arteritis) were initially treated using prednisone (40-60 mg daily). The response was good in all three, but each experienced exacerbation of symptoms and elevation of Westergren sedimentation rates (WSR) with dose reduction. The addition of methotrexate (7.5-12.5 mg/wk) resulted in diminished symptoms and lower WSR and proved to be steroid-sparing.

Report this publication

Statistics

Seen <100 times