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Method-specific serum cortisol responses to the adrenocorticotrophin test: comparison of gas chromatography-mass spectrometry and five automated immunoassays.

Authors
  • El-Farhan, Nadia
  • Pickett, Alan
  • Ducroq, David
  • Bailey, Catherine
  • Mitchem, Kelly
  • Morgan, Nicola
  • Armston, Annie
  • Jones, Laila
  • Evans, Carol
  • Rees, D Aled
Type
Published Article
Journal
Clinical endocrinology
Publication Date
May 01, 2013
Volume
78
Issue
5
Pages
673–680
Identifiers
DOI: 10.1111/cen.12039
PMID: 22994849
Source
Medline
License
Unknown

Abstract

Normal cortisol responses to the ACTH test are influenced significantly by assay and oestrogen treatment. We recommend the use of separate reference limits in premenopausal women on the OCP and warn users that cortisol measurements in this subgroup are subject to assay interference.

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