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[A method of searching for amphipathic structures in protein sequences].

Authors
  • Gabriélian, A E
  • Ivanov, V S
  • Kozhich, A T
Type
Published Article
Journal
Bioorganicheskaia khimiia
Publication Date
Jul 01, 1989
Volume
15
Issue
7
Pages
985–986
Identifiers
PMID: 2479384
Source
Medline
License
Unknown

Abstract

A simple method for searching amphipathic helices based on estimation of correlation between hydrophobicity distribution and periodic function is proposed. The method was examined in a series of proteins with known T-cell epitopes, which are mostly amphipathic helices. The predictive power of the method is discussed.

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