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A method for a quantitative determination of changes in tissue volume as a result of perfusion fixation.

Authors
  • Drenhaus, U
  • Schingnitz, G
  • Dorka, M
Type
Published Article
Journal
Anatomischer Anzeiger
Publication Date
Jan 01, 1986
Volume
161
Issue
4
Pages
327–332
Identifiers
PMID: 3526976
Source
Medline
License
Unknown

Abstract

A method for quantifying changes in volume of tissue as a result of perfusion fixation is described. This is achieved by setting standards into the tissue in vivo and in situ by applying dyes to the intact tissue at known distances. Immediately after perfusion the distances of the dyes are macroscopically measured and the comparison between the corresponding distances before and after perfusion enables a quantification of the alteration of the tissue. The total error of this method is approximately 0.5-0.8% (linear).

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