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Methemoglobinemia due to topical pharyngeal anesthesia during endoscopic procedures.

Authors
  • Vallurupalli, Srikanth1
  • 1 Southern Illinois University College of Medicine, Springfield, IL, USA.
Type
Published Article
Journal
Local and regional anesthesia
Publication Date
Jan 01, 2010
Volume
3
Pages
137–142
Identifiers
DOI: 10.2147/LRA.S12227
PMID: 22915882
Source
Medline
Keywords
License
Unknown

Abstract

Acquired methemoglobinemia is a known complication of topical anesthesia during endoscopic procedures. Benzocaine has been implicated in a majority of cases and has been removed from some hospital formularies. However, a lot of uncertainty exists about the risk factors for this uncommon complication. This review attempts to summarize the current knowledge of this condition and describe known risk factors. Anesthetic and patient-specific risk factors are described along with some hypothetical procedure-related factors. Clinicians should identify patients who are at high risk and apply appropriate postprocedure screening. Prospective studies are needed to further our knowledge and improve patient safety.

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