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METAPLASTIC CARCINOMA BREAST: A CASE SERIES

Authors
  • ijar journal
  • Rathod, Kalpana
  • ,
  • Arya, Vishakha
  • Shinde, Dhanshri
  • Nakate, Leena
  • ,
  • ,
  • ,
Type
Published Article
Journal
International Journal of Advanced Research
Publisher
International Journal Of Advanced Research
Publication Date
Jan 27, 2024
Volume
12
Issue
01
Pages
250–253
Identifiers
DOI: 10.21474/ijar01/18114
Source
MyScienceWork
Keywords
License
Green

Abstract

Introduction: Metaplastic breast carcinoma is a distinct histological type of breast cancer and comprises of two components ofboth epithelial & mesenchymal type in a single tumor. It includes adenosquamous, squamous cell carcinoma (SCC), spindle cell carcinoma, metaplastic carcinoma with mesenchymal differentiation, mixed carcinoma and myoepithelial carcinoma. Materials and Methods: The study comprises of 5 cases of Metaplastic Breast carcinoma and was conducted in the Department of Pathology in Western part of India. Discussion: MBC is characterized by adenocarcinoma admixed with spindle cells, squamous cells and mesenchymal differentiation. Among the five cases in the present series, two cases showed lymph nodes metastasis. Commonlyimmunohistochemistry (IHC) markers in cases of MBC shows triple negative for estrogen receptor (ER), progesterone receptor (PR) and HER2-neu. Conclusion: The MBC has a poor prognosis and have a diverse clinical behavior, variable histology and different regime of treatment.

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