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[Metabolism of liver polyphosphoisositides in rats during stimulating and depressing influences on the organism].

Authors
  • Kiselev, G V
  • Pavlinova, L I
Type
Published Article
Journal
Biulleten' eksperimental'noĭ biologii i meditsiny
Publication Date
Sep 01, 1975
Volume
80
Issue
9
Pages
40–43
Identifiers
PMID: 177130
Source
Medline
License
Unknown

Abstract

Under normal conditions the rate of the 32P-orthophosphate incorporation into the polyphosphoinositides was 30--40 times greater than into the other phospholipid fraction of the normal rat liver. There was a rapid postmortem alteration of the polyphosphoinositide content in the liver. Under conditions studied the changes in the phospholipid content were revealed in the polyphosphoinositide fractions only. The changes in the content and in the metabolic intensity of rat polyphosphoinositide in the liver were in many respects similar to those in the brain. Polyphosphoinositide fractions were found to be the most labile of all the phospholipid fractions in the rat liver.

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