SUMMARY The work was conducted to evaluate the metabolic profile of lactating goats fed diets containing integral mango meal as a replacement for corn. Four levels of replacement (0, 33, 66 and 100%) were evaluated in diets with forage:concentrate ratio of 60:40. Eight crossbred multiparous lactating Saanen goats (48.72 ± 1.99 kg of BW) were introduced in the experiment 48 days postpartum and maintained up to 124 days of lactation. It was used a double Latin Square (4x4) experimental design, with four treatments, four periods and four animals per square. There was no effects (P>0.05) for the integral mango meal level on the intake of DM (1890 g/day), CP (278 g/day) and NDF (959 g/day). However, the intake of NFC and TDN decreased (P<0.05) 27.9 g/day and 0.082 kg/day, respectively, as the dietary integral mango meal increased. The concentrations of urea, creatinine, gamma glutamyl transferase, aspartate aminotransferase, albumin, total protein, glucose, triglycerides, total cholesterol, and magnesium were not altered (P>0.05) by replacement levels, with average values of 54.52 mg/dl, 0.71 mg/dl, 52.59 UI, 77.37 UI, 4.69 g/dl, 9.32 g/dl, 74.44 mg/dl, 40.10 mg/dl, 39.39 mg/dl, and 11.09 mg/dl, respectively. Considering the metabolic profile, mango meal whole can totally replace corn in diets of dairy goats.