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On the metabolic characteristics of hybrids Shigella flexneri x Escherichia coli, devoid of their ability for intracellular multiplication in the epithelial cells. IV. Growth characteristics in the presence of some tricarboxylic acid cycle intermediates.

Authors
  • Radoutcheva, T
  • Veljanov, D
  • Bondarenko, V M
Type
Published Article
Journal
Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie
Publication Date
Sep 01, 1978
Volume
241
Issue
3
Pages
319–324
Identifiers
PMID: 364886
Source
Medline
License
Unknown

Abstract

The dynamics of avirulent xyl-str and xyl + hybrids Sh. flexneri was investigated in minimal medium in the presence of some tricarboxylic acid cycle intermediates (succinate, malate, fumarate) and pyruvate. It was established that the hybrids with a replaced xyl-str or xyl-region show a considerably lower rate of multiplication in artificial media than the virulent recipient strains.

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