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Meta-analysis and meta-modelling for diagnostic problems.

Authors
  • Charoensawat, Suphada
  • Böhning, Walailuck
  • Böhning, Dankmar
  • Holling, Heinz
Type
Published Article
Journal
BMC Medical Research Methodology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2014
Volume
14
Pages
56–56
Identifiers
DOI: 10.1186/1471-2288-14-56
PMID: 24758534
Source
Medline
License
Unknown

Abstract

The proposed methodology allows us to embed the meta-analysis of diagnostic studies into the well-developed area of mixed modelling. Different outcome measures, specifically from the perspective of whether a local or a global measure of diagnostic accuracy should be applied, are discussed as well. In particular, variation in cut-off value is discussed together with recommendations on choosing the best cut-off value. We also show how this problem can be addressed with the proposed methodology.

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