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Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy.

Authors
  • Han, Zhipeng
  • Jing, Yingying
  • Xia, Yong
  • Zhang, Shanshan
  • Hou, Jing
  • Meng, Yan
  • Yu, Fenghai
  • Liu, Xiaoqing
  • Wu, Mengchao
  • Zhang, Ping
  • Wei, Lixin
Type
Published Article
Journal
Cell & Bioscience
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2014
Volume
4
Pages
22–22
Identifiers
DOI: 10.1186/2045-3701-4-22
PMID: 24872873
Source
Medline
Keywords
License
Unknown

Abstract

These results suggest that increase in TGF-β expression by MSCs in the inflammatory microenvironment of HCC promotes the development of chemoresistance in HCC cells.

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