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Merogony of Toxoplasma gondii (Apicomplexa: Coccidia) and its effect on the mortality and histopathology in the house mouse Mus musculus.

Authors
  • Fayed, Hamed M
  • Allam, Kamilia A M
  • Ali, Nour-Eldin Shams-Eldin
Type
Published Article
Journal
Journal of the Egyptian Society of Parasitology
Publisher
"Al Manhal FZ, LLC"
Publication Date
Apr 01, 2004
Volume
34
Issue
1
Pages
45–64
Identifiers
PMID: 15125516
Source
Medline
License
Unknown

Abstract

Merogonic stages of Toxoplasma gondii, their effects on the mortality and histopathological changes in the orally-inoculated male house mice Mus musculus with low and high doses (LD&HD) of T. gondii sporulated oocysts was investigated. The mortality percentage in LD group was 16%, 20%, 28% and 72%, while that in HD group was 36%, 56%, 72% and 100% in the 1st-4th week, respectively. Meanwhile, the maximum mortality percentage of the control group reached 6%. The histopathological changes induced by the parasite in different organs such as kidneys, liver, brain, spleen, heart, lungs and testes were discussed.

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