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The merged basins of signal transduction pathways in spatiotemporal cell biology.

Authors
  • Hou, Yingchun
  • Hou, Yang
  • He, Siyu
  • Ma, Caixia
  • Sun, Mengyao
  • He, Huimin
  • Gao, Ning
Type
Published Article
Journal
Journal of Cellular Physiology
Publisher
Wiley (John Wiley & Sons)
Publication Date
Mar 01, 2014
Volume
229
Issue
3
Pages
287–291
Identifiers
DOI: 10.1002/jcp.24449
PMID: 23939989
Source
Medline
License
Unknown

Abstract

Numerous evidences have indicated that a signal system is composed by signal pathways, each pathway is composed by sub-pathways, and the sub-pathway is composed by the original signal terminals initiated with a protein/gene. We infer the terminal signals merged signal transduction system as "signal basin". In this article, we discussed the composition and regulation of signal basins, and the relationship between the signal basin control and triple W of spatiotemporal cell biology. Finally, we evaluated the importance of the systemic regulation to gene expression by signal basins under triple W. We hope our discussion will be the beginning to cause the attention for this area from the scientists of life science.

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