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MEN syndromes.

Authors
  • Falchetti, Alberto
Type
Published Article
Journal
Tumori
Publication Date
Jan 01, 2010
Volume
96
Issue
5
Pages
823–826
Identifiers
PMID: 21302639
Source
Medline
License
Unknown

Abstract

MEN1 and MEN2 are rare inherited cancer syndromes which express a variety of endocrine and nonendocrine tumors. The improved knowledge of molecular and clinical physiopathology of MEN syndromes, together with the availability of genetic testing, have led to earlier detection and intervention, with consequent reduction of mortality and morbidity for MEN-associated tumors. Genetic testing has gained a key role in the detection of asymptomatic patients harbouring mutations responsible for these syndrome, and allows institution of early and tailored intervention with a positive impact on the course of disease.

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