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Medication use patterns and predictors of nonpersistence and nonadherence with oral 5-aminosalicylic acid therapy in patients with ulcerative colitis.

Authors
  • Yen, Linnette
  • Wu, Joanne
  • Hodgkins, Pau L
  • Cohen, Russell D
  • Nichol, Michael B
Type
Published Article
Journal
Journal of managed care pharmacy : JMCP
Publication Date
Jan 01, 2012
Volume
18
Issue
9
Pages
701–712
Identifiers
PMID: 23206213
Source
Medline
License
Unknown

Abstract

Patients on once-daily dosed Multi-Matrix System mesalamine had the lowest risk of discontinuation and the highest adherence rate. Multiple factors were associated with either nonpersistence or nonadherence, including multiple-daily dosed index medication, younger age, female gender, residing in the South region, PPO plan, noncommercial payer, not using immunosuppressive/biologic agents, not using rectal 5-ASA, and never receiving specialist care.

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