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Are Medication Swallowing Lubricants Suitable for Use in Dysphagia? Consistency, Viscosity, Texture, and Application of the International Dysphagia Diet Standardization Initiative (IDDSI) Framework

Authors
  • Malouh, Marwa A.1
  • Cichero, Julie A.Y.1, 2
  • Manrique, Yady J.1
  • Crino, Lucia1
  • Lau, Esther T. L.1, 2
  • Nissen, Lisa M.1, 2
  • Steadman, Kathryn J.1, 2
  • 1 (L.M.N.)
  • 2 School of Clinical Sciences, Queensland University of Technology, Brisbane, QLD 4001, Australia
Type
Published Article
Journal
Pharmaceutics
Publisher
MDPI
Publication Date
Sep 28, 2020
Volume
12
Issue
10
Identifiers
DOI: 10.3390/pharmaceutics12100924
PMID: 32998301
PMCID: PMC7601516
Source
PubMed Central
Keywords
Disciplines
  • Article
License
Green

Abstract

Medication lubricants are thick liquids or gels that are designed to aid swallowing of solid oral dosage forms. Tablets and capsules are placed within a spoonful of the product for swallowing. The aim of this study was to describe and compare commercially available medication lubricants in terms of textural suitability for patients with dysphagia. Twelve medication lubricants were characterised according to the International Dysphagia Diet Standardisation Initiative (IDDSI) framework. Apparent viscosity, yield stress, thickness consistency, and various texture features were compared. Gloup Forte was the only medication lubricant classified as IDDSI level 4 (pureed/extremely thick) at room (24 °C) temperature. Four other Gloup products were IDDSI level 3 (liquidised/moderately thick) at room temperature but testing at 4 °C or pouring from the container instead of using the pump dispenser resulted in classification as IDDSI level 4. The IDDSI Flow test would have classified MediSpend and Slo Tablets as IDDSI level 3, but their very low yield stress led to these fluids flowing too quickly through the prongs of a fork and so these were classified as <3. Severo was IDDSI level 2. Heyaxon and the two versions of Magic Jelly tested contained lumps, and Swallow Aid had exceptionally high viscosity, hardness, adhesiveness, and gumminess, classifying them as IDDSI Level 7 (“regular textures”) and therefore as unsuitable for people with dysphagia according to IDDSI. This study provides valuable information to help with the selection of a safe medication lubricant with appropriate thickness level suited to each individual with dysphagia.

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