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Medication non-adherence and its influencing factors in persons with schizophrenia in rural China.

Authors
  • Li, Xu-Hong1
  • Deng, Shu-Yu2
  • Zhang, Tian-Ming3
  • Wang, Yi-Zhou2
  • Wong, Irene Yin Ling4
  • Ran, Mao-Sheng2, 5
  • 1 Department of Social and Behavioural Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China. , (China)
  • 2 Department of Social Work and Social Administration, University of Hong Kong, Pok Fu Lam, Hong Kong SAR, China. , (China)
  • 3 Department of Social Work, Shanghai University, Shanghai, China. , (China)
  • 4 School of Social Policy & Practice, University of Pennsylvania, Philadelphia, PA, USA.
  • 5 Mental Health Center, West China Hospital, Sichuan University, Chengdu, China. , (China)
Type
Published Article
Journal
Journal of mental health (Abingdon, England)
Publication Date
Feb 01, 2024
Volume
33
Issue
1
Pages
40–47
Identifiers
DOI: 10.1080/09638237.2022.2140789
PMID: 36322512
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Few studies have been conducted to explore medication non-adherence in persons with schizophrenia (PWS) and its influencing factors in rural China. This study aimed to investigate the medication non-adherence and its influencing factors among PWS in rural China. A total of 269 PWS and their family caregivers in Xinjin district, Chengdu, China were investigated on medication adherence and related factors. Logistic regression was employed to identify the influencing factors. The results showed that 37.6% of PWS had medication non-adherence. PWS living with family caregivers had significantly lower rate of medication non-adherence (34.7%) than those not living with family caregivers (60.0%) (p < 0.01). Family caregivers' affiliate stigma of mental illness, knowledge of mental illness and self-esteem were significantly related to patients' medication non-adherence (p < 0.05). PWS' employment status, living with family caregiver, present mental status and social support were significantly related to medication adherence. This study shows medication non-adherence is severe among PWS in rural China. Both patient- and family-related factors affect patients' medication adherence seriously. Except improving patients' treatment and mental status, development of family caregiving, social support network and intervention on reducing stigma of mental illness should be crucial for enhancing PWS' medication adherence.

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