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Median nerve conduction studies in rabbits

Authors
  • Mansiz-Kaplan, Basak1
  • Pervane-Vural, Secil1
  • Gursoy, Koray1
  • Nacir, Baris1
  • 1 University of Health Sciences, Ankara, Turkey , Ankara (Turkey)
Type
Published Article
Journal
BMC Neuroscience
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Aug 17, 2020
Volume
21
Issue
1
Identifiers
DOI: 10.1186/s12868-020-00584-2
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundWhen planning nerve conduction studies using animal models, the sciatic nerve is often used and the upper extremity nerves are not preferred due to the size of laboratory animals. This study aimed to present the method and mean values of median nerve conduction studies in laboratory rabbits. Fifty-five six-month-old male New Zealand white rabbits weighing 2 to 2.5 kg were included in nerve conduction studies performed under anesthesia. The compound muscle action potential amplitude and distal latency values were recorded for the median motor nerve with the electrodes placed on the flexor digitorum superficialis muscle and tendon.ResultsA total of 110 median nerves were evaluated. The mean amplitude of the median nerve was 30.6 ± 6.8, mV the median nerve distal latency was 1.3 ± 0.2 ms, and the mean intensity of stimulation inducing a response was 2.5 ± 1 mA.ConclusionsThe mean values obtained by the median motor nerve conduction method in this study can act as a guide for future nerve interventions undertaken in the upper extremities.

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