Affordable Access

Mechanobactericidal Nanotopography on Nitrile Surfaces toward Antimicrobial Protective Gear

Authors
  • Patil, Deepak
  • Golia, Vibhanshu
  • Overland, Maya
  • Stoller, Marshall
  • Chatterjee, Kaushik
Publication Date
Feb 21, 2023
Source
eScholarship - University of California
Keywords
License
Unknown
External links

Abstract

We have much to learn from other living organisms when it comes to engineering strategies to combat bacterial infections. This study describes the fabrication of cicada wing-inspired nanotopography on commercially pure (CP) nitrile sheets and nitrile gloves for medical use using the reactive ion etching (RIE) technique. Antibacterial activity against P. aeruginosa was tested using two different surface morphologies. It was observed that the etched nitrile surfaces effectively minimized bacterial colonization by inducing membrane damage. Our findings demonstrate a single-step dry etching method for creating mechanobactericidal topographies on nitrile-based surfaces. These findings have utility in designing next-generation personal protective gear in the clinical setting and for many other important applications in the age of antimicrobial resistance.

Report this publication

Statistics

Seen <100 times