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Mechanistic Biomarkers in Toxicology

Authors
  • SANAJOU, Sonia1
  • ŞAHİN, Gönül1
  • 1 Faculty of Pharmacy, Eastern Mediterranean University, 99628, Famagusta, North Cyprus, Via Mersin 10, Turkey
Type
Published Article
Journal
Turkish Journal of Pharmaceutical Sciences
Publisher
Galenos Publishing
Publication Date
Jun 18, 2021
Volume
18
Issue
3
Pages
376–384
Identifiers
DOI: 10.4274/tjps.galenos.2020.10270
PMID: 34157829
PMCID: PMC8231318
Source
PubMed Central
Keywords
Disciplines
  • Review
License
Unknown

Abstract

Biomarkers are important parameters that are reliable, applicable, reproducible, and generally inexpensive. All biomarkers have a significant role in human health, especially mechanistic biomarkers, which are the most important for the prevention of toxic effects and diseases. They demonstrate the possibility of diagnosis, prognosis, recurrence, and spread of disease. Furthermore, they show the exposure levels to numerous chemical, biological, and physical agents. To date, the development and application of biomarkers require the knowledge of mechanisms underlying their production. Therefore, the present study focused on the possible mechanistic biomarkers.

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