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Mechanisms leading to toxin-induced impairment of renal function, with a focus on immunopathology.

Authors
  • Weening, J J
Type
Published Article
Journal
Toxicology Letters
Publisher
Elsevier
Publication Date
Mar 01, 1989
Volume
46
Issue
1-3
Pages
205–211
Identifiers
PMID: 2650027
Source
Medline
License
Unknown

Abstract

Environmental, occupational and therapeutic exposure to nephrotoxic compounds may cause different forms of renal disease and constitutes a major health problem. This paper discusses pathogenetic mechanisms leading to impairment of renal function and early detection of its symptoms, with special emphasis on immunopathology. Finally, it focuses on ways of identifying potentially nephrotoxic compounds.

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