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[Mechanisms of the hemodynamic effects of nonachlazine in ischemic heart disease patients].

Authors
  • Zaslavskaia, R M
  • Zolotaia, R D
  • Olevskiĭ, I Kh
  • Duda, S G
  • Vilkovyskiĭ, F A
Type
Published Article
Journal
Farmakologiia i toksikologiia
Publication Date
Jan 01, 1986
Volume
49
Issue
6
Pages
73–77
Identifiers
PMID: 3817152
Source
Medline
License
Unknown

Abstract

During course therapy with nonachlazine of patients with ischemic heart disease, stable angina pectoris a negative inotropic effect of the drug in persons with eukinetic and in particular hyperkinetic type of hemodynamics was revealed. Enhancement of beta-adrenoblocking effect of nonachlazine with an increase of its daily dose was found. Nonachlazine effect on hemodynamic parameters was shown to be mediated through adrenoreactive structures.

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