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Mechanisms of Bacterial Cell Division

Authors
  • Vedyaykin, A. D.
  • Ponomareva, E. V.
  • Khodorkovskii, M. A.
  • Borchsenius, S. N.
  • Vishnyakov, I. E.
Type
Published Article
Journal
Microbiology
Publisher
Pleiades Publishing
Publication Date
May 01, 2019
Volume
88
Issue
3
Pages
245–260
Identifiers
DOI: 10.1134/S0026261719030159
Source
Springer Nature
Keywords
License
Yellow

Abstract

Abstract—Despite numerous studies, gaps still remain in our understanding of bacterial cell division. This review describes the basic mechanisms responsible for division of the bacterial cell and coordination of this process in space and time. Attention is concentrated on such well-studied, model microorganisms as gram-negative bacteria Escherichia coli and gram-positive Bacillus subtilis. The hypothetical models of cell division of mycoplasmas which lack a cell wall and have lost most of the genes encoding the homologs of the known components of the bacterial divisome are also considered. Due to the fact that the bacterial division apparatus is a promising target for new antibiotics, the investigation of this process, apart from basic importance, is also of applied interest, and therefore is one of the priorities of modern molecular microbiology.

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