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Mechanism for transfer of transposon Tn2010 carrying macrolide resistance genes in Streptococcus pneumoniae and its effects on genome evolution.

Authors
  • Zhou, Wenqing
  • Yao, Kaihu
  • Zhang, Gang
  • Yang, Yonghong
  • Li, Yun
  • Lv, Yuan
  • Feng, Jie
Type
Published Article
Journal
Journal of Antimicrobial Chemotherapy
Publisher
Oxford University Press
Publication Date
Jun 01, 2014
Volume
69
Issue
6
Pages
1470–1473
Identifiers
DOI: 10.1093/jac/dku019
PMID: 24532683
Source
Medline
Keywords
License
Unknown

Abstract

Tn2010 tended to be transferred by transformation rather than conjugation in S. pneumoniae, and the spread of Tn2010 could have a profound effect on the evolution of the genome. The acquisition of Tn2010 with negligible fitness cost may facilitate spread of the transposon.

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