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Mechanical property predictions for polymorphs of sulphathiazole and carbamazepine.

Authors
  • Roberts, R J
  • Payne, R S
  • Rowe, R C
Type
Published Article
Journal
European Journal of Pharmaceutical Sciences
Publisher
Elsevier
Publication Date
Jan 01, 2000
Volume
9
Issue
3
Pages
277–283
Identifiers
PMID: 10594385
Source
Medline
License
Unknown

Abstract

The mechanical properties of polymorphs of sulphathiazole and carbamazepine have been determined experimentally by three-point beam bending. It is shown that the mechanical properties of sulphathiazole and carbamazepine polymorphs can be predicted using the atom-atom potential model applied to lattice dynamics, as long as account is taken of crystal morphology when considering the experimental results.

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