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Measurement of hepatic blood flow in the unanesthetized rabbit using 198Au and 125I Rose Bengal clearance technique.

Authors
Type
Published Article
Journal
Biomedicine / [publiée pour l'A.A.I.C.I.G.]
Publication Date
Volume
23
Issue
9
Pages
353–355
Identifiers
PMID: 1231933
Source
Medline
License
Unknown

Abstract

Hepatic blood flow was measured in the unanesthetized rabbit using the clearance technique of 198Au and 125I RB. The values are: 71.82 +/- 16.24 ml-min-1-kg-1 for 198Au, and 60.21+/-9.94 ml-min-1-kg-1 for 125I RB (P less than 0.01). The overestimation of HBF with colloidal gold is probably due to extra splanchnic sequestration which has been estimated to be 15+/-3%. The week extraction of RB limits the use of this dye for measurements of HBF. HBF is easier to measure with 198 Au.

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