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Measles, mumps, and rubella antibodies in children 5-6 years after immunization: effect of vaccine type and age at vaccination.

Authors
  • Boulianne, N
  • De Serres, G
  • Ratnam, S
  • Ward, B J
  • Joly, J R
  • Duval, B
Type
Published Article
Journal
Vaccine
Publisher
Elsevier
Publication Date
Nov 01, 1995
Volume
13
Issue
16
Pages
1611–1616
Identifiers
PMID: 8578850
Source
Medline
License
Unknown

Abstract

The levels of antibody against measles, mumps, and rubella were determined at 5-6 years postimmunization in 468 children vaccinated with two different trivalent vaccines. The proportions of children without detectable antibody levels were 12 and 3.6% for measles (p < 0.001), 14.9 and 7% for mumps (p = 0.006), and 3.3 and 3.1% for rubella (p = 0.88), respectively, in MMR II and Trivirix recipients. A higher proportion of those vaccinated at younger ages had undetectable or low levels of measles antibody. These data indicate that a large proportion of children vaccinated under routine conditions do not have detectable measles and mumps antibody.

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