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Mean platelet volume change (∆MPV) and red blood cell distribution width (RDW) as promising markers of community-acquired pneumonia (CAP) outcome

Authors
  • Farghly, Sahar1
  • Abd-Elkader, Randa1
  • El Zohne, Randa A.1
  • Abd El-Kareem, Doaa M.1
  • 1 Assiut University, Assiut, Egypt , Assiut (Egypt)
Type
Published Article
Journal
The Egyptian Journal of Bronchology
Publisher
Springer Berlin Heidelberg
Publication Date
Aug 20, 2020
Volume
14
Issue
1
Identifiers
DOI: 10.1186/s43168-020-00024-z
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundPrognostic markers play an essential role in the proper management of community-acquired pneumonia. This research work aimed to evaluate the association of RDW and /or MPV with mortality and morbidity in patients with CAP to improve the yield of already used prognostic scores.ResultsThe current study enrolled 153 patients with community-acquired pneumonia (CAP). Out of them, 101 (64%) patients improved while 52 (36%) died. It was noticed that each of delta MPV and RDW (P < 0.001) had positive significant correlation with PSI and CURB-65. Delta MPV and RDW was significantly higher in patients who died (2.61 ± 1.01 vs. 1.78 ± 0.76; P = 0.01 for delta MPV and 16.50 ± 3.54 vs. 15.50 ± 2.81; P = 0.02 for RDW).ConclusionInitial RDW and rising MPV during hospitalization for CAP is associated with more severe clinical characteristics and high mortality. Moreover, the use of RDW and delta MPV in patients admitted with CAP can improve the performance of prognostic scales.

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