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Maternal immunization to paternal antigens in multiparous mice.

Authors
  • Baines, M G
  • Ansell, J
  • McLaren, A
  • Micklem, H S
Type
Published Article
Journal
Journal of reproduction and fertility
Publication Date
Feb 01, 1975
Volume
42
Issue
2
Pages
293–299
Identifiers
PMID: 235026
Source
Medline
License
Unknown

Abstract

Mice of the CBA strain which had given birth to five litters sired by males of a different H-2 type (C57BL/10) showed evidence of immunization to paternal antigens, in that the numbers of lymphocytes forming alloclusters with paternal erythrocytes were significantly elevated. On the other hand, the graft-versus-host responsiveness of maternal splenic lymphocytes to paternal antigens remained virtually unchanged, showing only a slight increase at Day 8 of the assay.

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