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Mapping systemic lupus erythematosus heterogeneity at the single-cell level

Authors
  • Nehar-Belaid, Djamel1
  • Hong, Seunghee2
  • Marches, Radu1
  • Chen, Guo1
  • Bolisetty, Mohan1
  • Baisch, Jeanine2
  • Walters, Lynnette3
  • Punaro, Marilynn3, 4
  • Rossi, Robert J.1
  • Chung, Cheng-Han1
  • Huynh, Richie P.1
  • Singh, Prashant1
  • Flynn, William F.1
  • Tabanor-Gayle, Joy-Ann5
  • Kuchipudi, Navya5
  • Mejias, Asuncion6
  • Collet, Magalie A.1
  • Lucido, Anna Lisa1
  • Palucka, Karolina1
  • Robson, Paul1, 5
  • And 5 more
  • 1 The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA , Farmington (United States)
  • 2 Weill Cornell Medicine, New York, NY, USA , New York (United States)
  • 3 Texas Scottish Rite Hospital for Children, Dallas, TX, USA , Dallas (United States)
  • 4 UT Southwestern Medical Center, Dallas, TX, USA , Dallas (United States)
  • 5 University of Connecticut School of Medicine, Farmington, CT, USA , Farmington (United States)
  • 6 Division of Pediatric Infectious Diseases, Nationwide Children’s Hospital and the Ohio State University School of Medicine, Columbus, OH, USA , Columbus (United States)
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
Aug 03, 2020
Volume
21
Issue
9
Pages
1094–1106
Identifiers
DOI: 10.1038/s41590-020-0743-0
Source
Springer Nature
License
Yellow

Abstract

Banchereau and colleagues provide a resource dataset that examines disease-related transcriptional profiles of peripheral whole-blood cells from adolescent patients with SLE by single-cell RNA-seq analysis.

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