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MAP1B is required for Netrin 1 signaling in neuronal migration and axonal guidance.

Authors
  • 1
Type
Published Article
Journal
Current Biology
0960-9822
Publisher
Elsevier
Publication Date
Volume
14
Issue
10
Pages
840–850
Identifiers
PMID: 15186740
Source
Medline

Abstract

These data indicate that MAP1B phosphorylation is controlled by Netrin 1 and that the lack of MAP1B impairs Netrin 1-mediated chemoattraction in vitro and in vivo. Thus, MAP1B may be a downstream effector in the Netrin 1-signaling pathway.

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