MAP1B is required for Netrin 1 signaling in neuronal migration and axonal guidance.
Developmental Neurobiology and Regeneration Unit, Institut de Recerca Biomedica de Barcelona, Barcelona Science Park and Department of Cell Biology, University of Barcelona, Barcelona 08028, Spain.
- Published Article
- Publication Date
May 25, 2004
These data indicate that MAP1B phosphorylation is controlled by Netrin 1 and that the lack of MAP1B impairs Netrin 1-mediated chemoattraction in vitro and in vivo. Thus, MAP1B may be a downstream effector in the Netrin 1-signaling pathway.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/15186740