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Malignant mesothelioma of the tunica vaginalis testis in a dog: histological and immunohistochemical characterization.

Authors
  • Vascellari, Marta1
  • Carminato, Antonio
  • Camali, Giovanni
  • Melchiotti, Erica
  • Mutinelli, Franco
  • 1 Histopathology Department, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padua, Italy. , (Italy)
Type
Published Article
Journal
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Publication Date
Jan 01, 2011
Volume
23
Issue
1
Pages
135–139
Identifiers
PMID: 21217045
Source
Medline
Language
English
License
Unknown

Abstract

Histologic and immunohistochemical features of a malignant mesothelioma of the testicular tunica vaginalis in a 9-year-old male mixed-breed dog are reported. The dog had a large scrotal swelling determined by ultrasonography to be a heterogeneous irregular mass characterized by a mixed echogenic pattern and located in the left vaginal canal of the testis. Histologically, the neoplasm was nodular, was poorly demarcated, and consisted of pleomorphic cells that were associated with a significant desmoplastic reaction. By immunohistochemistry, neoplastic cells stained positively for cytokeratin and vimentin and were immunoreactive with an antimesothelial cell monoclonal antibody. Malignant mesotheliomas of tunica vaginalis testis are rare in mammalian species, including dogs.

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