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Malignant fibrous histiocytoma.

Authors
  • Hughes, J P
  • Mills, N L
  • Lynch, R C
  • Setze, T K
Type
Published Article
Journal
Southern medical journal
Publication Date
Oct 01, 1975
Volume
68
Issue
10
Pages
1219–1222
Identifiers
PMID: 170688
Source
Medline
License
Unknown

Abstract

Two patients are presented who had malignant fibrous histiocytomas of the skin and soft tissue. These tumors characteristically consist of a solitary mass, 0.5 cm to 12.0 cm, which has skin fixation, is circumscribed and firm. Microscopically, there is a pattern of histiocytes and bizarre histiocytic giant cells intermingled in a fibrous stroma with fibroblasts arranged in a whirling pattern. The lesion is treated with wide excision and skin grafting. Local recurrence is common. Metastasis is less common, but with metastasis the prognosis is poor.

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