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A male-specific DNA probe detects heterochromatin sequences in a familial Yq- chromosome.

Authors
Type
Published Article
Journal
American journal of human genetics
Publication Date
Volume
36
Issue
6
Pages
1394–1396
Identifiers
PMID: 6517059
Source
Medline

Abstract

Using a recombinant DNA probe, we have demonstrated the presence of residual 3.4-kilobase (kb) repeat sequences in a family with a Yq- chromosome. The heterochromatin of this Y variant was not readily detectable with conventional chromosome-banding techniques. These data suggest that the breakpoint of the deletion occurs at the heterochromatin region proximal to the euchromatin/heterochromatin junction.

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