Affordable Access

Publisher Website

Making a diagnosis of VWD.

Authors
Type
Published Article
Journal
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program
Publication Date
Volume
2012
Pages
161–167
Identifiers
DOI: 10.1182/asheducation-2012.1.161
PMID: 23233576
Source
Medline

Abstract

A clear understanding of the molecular basis of VWD can guide the choice and interpretation of appropriate diagnostic tests. This review briefly describes the lifecycle and molecular interactions of VWF and how they lead to the current clinical classification. It also includes a brief discussion of the differential diagnosis and general workup of mucocutaneous bleeding, a review of the various VWD subtypes, and pertinent laboratory assays for each, including genetic tests. Finally, common testing pitfalls and diagnostic dilemmas are covered, including the challenge created by the overlap of borderline low VWF levels and mild bleeding.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments