Affordable Access

Making agonists of antagonists.

Authors
Type
Published Article
Journal
Chemistry & Biology
1074-5521
Publisher
Elsevier
Publication Date
Volume
1
Issue
3
Pages
125–129
Identifiers
PMID: 9383381
Source
Medline
License
Unknown

Abstract

Cell-surface receptors can be divided into three classes, depending on whether they transmit information by allosteric conformational change, by receptor dimerization, or by receptor aggregation. So far, only the first class of receptors has proven readily accessible to chemical techniques; this is no accident, but times are changing.

Statistics

Seen <100 times