Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Magneto-optical characteristics of human sperms: normal and deformed.

Authors
  • Sakhnini, Lama1
  • Dairi, Maheen
  • Manaa, Hacene
  • 1 Physics Department, College of Science, University of Bahrain, P. O. Box 32038, Sakhir, Kingdom of Bahrain. [email protected] , (Bahrain)
Type
Published Article
Journal
Journal of Biophotonics
Publisher
Wiley (John Wiley & Sons)
Publication Date
Aug 01, 2008
Volume
1
Issue
3
Pages
238–244
Identifiers
DOI: 10.1002/jbio.200810002
PMID: 19412973
Source
Medline
License
Unknown

Abstract

In this study we report on magnetic orientation of human sperms. Samples were taken from 17 donors. Normal human sperms became oriented with their long axis perpendicular to the magnetic field (1 T maximum). Total orientation was achieved with magnetic field of about 1 T, while for abnormal sperms the magnetic behavior was different. The dependence of the measured degree of orientation on the intensity of the magnetic field was in good agreement with the theoretical equation for the magnetic orientation of diamagnetic substances. As a result of a numerical analysis based on the equation, the anisotropic diamagnetic susceptibility of normal sperm was found to be Delta(chi) = 8 x 10(-20) J/T(2). The degree of orientation was influenced by the alterations in the shape of the head, body or the tail. It has been suggested that the DNA in the sperm head retain the strong magnetic anisotropy to counterbalance the magnetic anisotropy retained by flagellum microtubules. Recent studies demonstrated a well-defined nuclear architecture in human sperm nucleus, where the head morphology has significant correlation with sperm chromatin structure assay SCSA. Then, as the methods to evaluate SCSA can be difficult and expensive our simple magnetic orientation technique can be an alternative to diagnose alteration in DNA.

Report this publication

Statistics

Seen <100 times