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Magnetic tagging of therapeutic cells for MRI.

Authors
  • Budde, Matthew D
  • Frank, Joseph A
Type
Published Article
Journal
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Publication Date
Feb 01, 2009
Volume
50
Issue
2
Pages
171–174
Identifiers
DOI: 10.2967/jnumed.108.053546
PMID: 19164242
Source
Medline
License
Unknown

Abstract

Transplantation of stem cells or immune cells has shown promise for the treatment of several diseases. Monitoring magnetically labeled cells with MRI has furthered our understanding of cellular migration and the pathophysiology of diseases in experimental models. These studies should pave the way for guiding clinical trials using cell-based therapies. This review briefly describes the various methods used to label and track cells with MRI and the potential for such methods to translate to human applications.

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