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Magnetic particle targeting for diagnosis and therapy of lung cancers

Authors
  • Saadat, Mahsa1
  • Manshadi, Mohammad K.D.2, 1
  • Mohammadi, Mehdi1, 2, 3, 4
  • Zare, Mohammad Javad5
  • Zarei, Mohammad6
  • Kamali, Reza7
  • Sanati-Nezhad, Amir2, 3
  • 1 Department of Chemical Engineering, College of Engineering, Shahid Bahonar University of Kerman, Kerman, Iran
  • 2 Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Alberta T2N 1N4, Canada
  • 3 Center for Bioengineering Research and Education, University of Calgary, Calgary, Alberta T2N 1N4, Canada
  • 4 Department of Biological Science, University of Calgary, Alberta T2N 1N4, Canada
  • 5 Medical College, Islamic Azad University, Tehran, Iran
  • 6 Mitochondrial and Epigenomic Medicine, and Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
  • 7 Department of Mechanical Engineering, Shiraz University, 71345 Shiraz, Iran
Type
Published Article
Journal
Journal of controlled release : official journal of the Controlled Release Society
Publication Date
Sep 11, 2020
Volume
328
Pages
776–791
Identifiers
DOI: 10.1016/j.jconrel.2020.09.017
PMID: 32920079
PMCID: PMC7484624
Source
PubMed Central
Keywords
Disciplines
  • Review Article
License
Unknown

Abstract

• The physics and utility of magnetic particle targeting for diagnosis of lung cancer are presented. • The present magnetic drug targeting and delivery systems, for lung cancer therapy are reviewed. • The technical advantages and practical drawbacks of various magnetic drug delivery methods are highlighted. • The future pespective on improved magnetic drug delivery and targeting to lungs is presented.

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