Affordable Access

Magnesium ion activity in the mammalian endolymph measured with ion-selective microelectrodes.

Authors
  • Ikeda, K
  • Morizono, T
  • Kusakari, J
  • Takasaka, T
Type
Published Article
Journal
Archives of oto-rhino-laryngology
Publication Date
Jan 01, 1988
Volume
245
Issue
3
Pages
142–144
Identifiers
PMID: 3178561
Source
Medline
License
Unknown

Abstract

The free Mg++ concentration in endolymph was measured with Mg++-selective microelectrodes based on the neutral ligand ETH 1117. The property of Mg++ microelectrodes was obtained from calibration solutions, containing various Mg++ concentrations with the background electrolytes resembling endolymph. The range between 10 and 0.1 mM Mg++ concentrations changed the potentials of Mg++ microelectrodes by 14.4 +/- 3.0 mV. The endocochlear potential and the Mg++ concentration in the endolymph were 82.0 +/- 5.0 mV and 0.77 +/- 0.29 mM in the guinea pig, and 84.4 +/- 4.9 mV and 1.12 +/- 0.24 mM in the chinchilla, respectively. These results are discussed in the light of the dependence of Na+, K+-ATPase and its interaction with Ca++.

Report this publication

Statistics

Seen <100 times