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The macrophage content of some human tumours.

Authors
  • Gauci, C L
  • Alexander, P
Type
Published Article
Journal
Cancer Letters
Publisher
Elsevier
Publication Date
Sep 01, 1975
Volume
1
Issue
1
Pages
29–32
Identifiers
PMID: 1235056
Source
Medline
License
Unknown

Abstract

The number of macrophages present in 44 surgically removed breast tumours and melanomas was determined by making a cell suspension and measuring the proportion of cells which bound a heterologous anti-macrophage serum and spread rapidly in culture. The macrophage content of the different tumours ranged from 0% to 30%. The malignant tumours which were known to have metastasized, as well as metastatic lesions, all contained less than 10% of macrophages whereas cancers for which there was no evidence of spread at operation had widely varying numbers of macrophages.

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