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[Macroergic phosphates in the brain under hypoxia].

Authors
  • Khvatova, E M
  • Mironova, G V
  • Shvets, N A
  • Seroglazova, G S
Type
Published Article
Journal
Voprosy medit︠s︡inskoĭ khimii
Publication Date
Jan 01, 1976
Volume
22
Issue
4
Pages
493–497
Identifiers
PMID: 1027235
Source
Medline
License
Unknown

Abstract

Acute hypoxic hypoxia ("height" 7000 m) did not cause distinct alterations in content of adenyl and guanyl nucleotides from brain tissue. Negative alterations in the pool of macroergic phosphates occurred in a deficit of oxygen ("height" 8000 m). Short-term training with hypoxia prevented the alterations in nucleotide pool even if the extreme hypoxia was applied ("height" 9000 m). Pre-cooling of animals promoted the maintenance of nucleotide pool at the "height" of 8000 and 9000 m. Hypothermia did not protect against the distinct alterations in content of both adenyl and guanyl nucleotides under conditions of oxygen deficit ("height" 9500 m and 1100 m).

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