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Lycopene attenuates LPS-induced TNF-α secretion in macrophages and inflammatory markers in adipocytes exposed to macrophage-conditioned media.

Authors
  • Marcotorchino, Julie
  • Romier, Beatrice
  • Gouranton, Erwan
  • Riollet, Celine
  • Gleize, Beatrice
  • Malezet-Desmoulins, Christiane
  • Landrier, Jean-François
Type
Published Article
Journal
Molecular Nutrition & Food Research
Publisher
Wiley (John Wiley & Sons)
Publication Date
May 01, 2012
Volume
56
Issue
5
Pages
725–732
Identifiers
DOI: 10.1002/mnfr.201100623
PMID: 22648619
Source
Medline
License
Unknown

Abstract

These data indicate that lycopene displayed an anti-inflammatory effect on macrophages that beneficially impacted adipocyte function. Thus, these results suggest that lycopene could block the vicious cycle that occurs between adipocytes and macrophages in adipose tissue during obesity.

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