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Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice.

Authors
  • Ip, Blanche C
  • Liu, Chun
  • Lichtenstein, Alice H
  • von Lintig, Johannes
  • Wang, Xiang-Dong
Type
Published Article
Journal
Journal of Nutrition
Publisher
Oxford University Press
Publication Date
Feb 01, 2015
Volume
145
Issue
2
Pages
268–276
Identifiers
DOI: 10.3945/jn.114.200238
PMID: 25644347
Source
Medline
Keywords
License
Unknown

Abstract

Our data suggest that lycopene and APO10LA inhibit HSFD-induced steatosis in BCO2-KO male mice through differential mechanisms. Sex disparity of BCO2-KO mice was observed in the outcomes of HSFD-induced liver steatosis and plasma lipids.

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