Affordable Access

deepdyve-link
Publisher Website

Lung cancer risk at low cumulative asbestos exposure: meta-regression of the exposure-response relationship.

Authors
  • van der Bij, Sjoukje
  • Koffijberg, Hendrik
  • Lenters, Virissa
  • Portengen, Lützen
  • Moons, Karel G M
  • Heederik, Dick
  • Vermeulen, Roel C H
Type
Published Article
Journal
Cancer Causes & Control
Publisher
Springer-Verlag
Publication Date
Jan 01, 2013
Volume
24
Issue
1
Pages
1–12
Identifiers
DOI: 10.1007/s10552-012-0107-7
PMID: 23187858
Source
Medline
License
Unknown

Abstract

The natural spline regression model indicates that at lower asbestos exposure levels, the increase in RR of lung cancer due to asbestos exposure may be larger than expected from previous meta-analyses. Observed potency differences between different fiber types are lower than the generally held consensus. Low-exposed industrial or population-based cohorts with quantitative estimates of asbestos exposure a required to substantiate the risk estimates at low exposure levels from our new, flexible meta-regression.

Report this publication

Statistics

Seen <100 times