Affordable Access

Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele.

Authors
Type
Published Article
Journal
Archives of Neurology
0003-9942
Publisher
American Medical Association
Publication Date
Volume
51
Issue
12
Pages
1189–1192
Identifiers
PMID: 7986172
Source
Medline
License
Unknown

Abstract

The apoE epsilon 4 allele may be associated with decreased cognitive function in discordant twin pairs. Our results suggest that epsilon 4 may represent a potential marker for accelerated cognitive aging and such individuals may be at greater risk for development of late-onset Alzheimer dementia or multi-infarct dementia.

Statistics

Seen <100 times